Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 144
interventional 117
Observational 26
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 50
Procedure 22
Drug|placebo 18
Other 6
Device 5
Drug|Other 5
Drug|Procedure 3
placebo|Procedure 2
Behavioral 1
Biological|Drug 1
Biological|Drug|Other 1
Diagnostic Test 1
Dietary Supplement|Drug 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
Netherlands 14
United States 13
United Kingdom 11
China 9
Korea, Republic of 9
NA 6
Turkey 6
France 4
Italy 4
Sweden 3
Switzerland 3
United States|Canada 3
Belgium 2
Canada 2
Denmark 2
Poland 2
Spain 2
Taiwan 2
Thailand 2
Austria 1
Austria|Belgium|Czech Republic|Denmark|Germany|Lithuania|Netherlands|Poland|Romania|Sweden|Switzerland 1
Austria|Denmark|Slovenia|Sweden 1
Belarus 1
Belarus|Russian Federation 1
Chile 1
Denmark|France|Norway|Sweden 1
Denmark|Serbia|Spain|United Kingdom 1
Egypt 1
Germany 1
Greece 1
Iran, Islamic Republic of 1
Japan 1
Norway 1
Russian Federation 1
Singapore 1
United States|France|Italy|Spain 1
United States|Germany|Hungary|Poland 1

Sites per Study

Site_count Study_Count
1 94
2 10
3 2
4 1
5 2
7 1
9 1
10 1
11 1
16 1
30 1
32 1
35 1

Phase

Phase Study_Count
N/A 48
Phase 2 24
Phase 4 24
Phase 1/Phase 2 8
Phase 2/Phase 3 5
Phase 3 5
Phase 1 3

Number of Arms

Number_of_Arms Count_of_Studies
1 5
2 90
3 5
4 7
6 1
8 1
NA 8

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 12.0000 10.00000 30.00 13.000 80.0 40.0 10.00
1st Qu. 41.0000 10.00000 48.25 40.750 96.0 61.0 30.00
Median 60.0000 10.00000 65.00 75.000 120.0 175.0 51.50
Mean 224.4468 18.66667 83.75 128.125 165.6 693.6 57.75
3rd Qu. 112.5000 23.00000 85.75 132.000 242.0 192.0 64.75
Max. 5413.0000 36.00000 238.00 900.000 290.0 3000.0 220.00

Trial Group Type

group_type Group_Count
Experimental 104
Active Comparator 54
Placebo Comparator 45
No Intervention 23
Sham Comparator 11
NA 8
Other 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 101
Crossover Assignment 7
Single Group Assignment 7
Factorial Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 62
Prevention 38
Basic Science 8
NA 4
Diagnostic 2
Health Services Research 1
Screening 1
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
NA 5
United States 5
Netherlands 4
China 2
Turkey 2
Belgium 1
Canada 1
Denmark 1
Germany 1
Hungary 1
Russian Federation 1
Spain 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 24
2 1
5 1

Enrollment Metrics

Measure Observational
Min 10.0000
1st Qu 20.0000
Median 40.0000
Mean 289.1538
3rd Qu 215.0000
Max 5000.0000

Observation Model

observational_model Study_Count
Cohort 16
Case-Control 4
NA 2
Case-Crossover 1
Case-Only 1
Case Control 1
Defined Population 1

Time Perspective

time_perspective Study_Count
Prospective 19
Cross-Sectional 2
Retrospective 2
Cross-Sectional, Prospective 1
Other 1
NA 1

Registries

Studies by Country

Country Study_Count
United States 1

Sites per Study

Site_count Study_Count
1 1

Enrollment Metrics

Measure Registries
Min 70
1st Qu 70
Median 70
Mean 70
3rd Qu 70
Max 70

Registry Model

observational_model Study_Count
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03382301 Ciclosporin A Preconditioning for Renal Artery Stenosis https://ClinicalTrials.gov/show/NCT03382301 Recruiting Hospices Civils de Lyon 2022-11-30
NCT03378817 Hypothermic Oxygenated Machine Perfusion of Extended Criteria Kidney Allografts From Brain Death Donors https://ClinicalTrials.gov/show/NCT03378817 Completed University Hospital, Aachen 2019-09-30
NCT03318575 Remote Ischemic Conditioning Using the autoRIC https://ClinicalTrials.gov/show/NCT03318575 Recruiting CellAegis US, Inc. 2019-04-30
NCT03102723 Platelet Inhibition to Target Reperfusion Injury https://ClinicalTrials.gov/show/NCT03102723 Recruiting National Heart Centre Singapore 2020-07-31
NCT03031470 Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver Transplantation https://ClinicalTrials.gov/show/NCT03031470 Completed Dompé Farmaceutici S.p.A 2017-02-09
NCT02993484 The Role of Mitochondrial Respiration in the Cardioprotective Capacity of IPC in Diabetic and Non-diabetic Patients https://ClinicalTrials.gov/show/NCT02993484 Completed University of Aarhus 2019-02-01
NCT02984111 Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery https://ClinicalTrials.gov/show/NCT02984111 Completed Shahid Beheshti University of Medical Sciences 2017-01-31
NCT02830841 Liver Protection of RIPC in Pediatric Living Donor Liver Transplantation https://ClinicalTrials.gov/show/NCT02830841 Completed RenJi Hospital 2019-01-31
NCT02812901 Tolerance of Myocardium to Ischemia Injury https://ClinicalTrials.gov/show/NCT02812901 Completed University Hospital, Lille 2017-07-31
NCT02731651 Effect of Pneumoperitoneum on Human Ovary https://ClinicalTrials.gov/show/NCT02731651 Completed Ege University 2015-10-31
NCT02729155 Single-cycle Remote Ischemic Preconditioning and Postconditioning for Prevention of Contrast-Induced Nephropathy https://ClinicalTrials.gov/show/NCT02729155 Recruiting Phramongkutklao College of Medicine and Hospital 2020-05-31
NCT02649309 Single-cycle Remote Ischemic Preconditioning and Postconditioning (SCRIP) Trial https://ClinicalTrials.gov/show/NCT02649309 Recruiting Phramongkutklao College of Medicine and Hospital 2019-05-31
NCT02581618 Remote Ischemic Preconditioning in Elective Percutaneous Interventions https://ClinicalTrials.gov/show/NCT02581618 Completed Trakya University 2016-02-29
NCT02540447 Purge Vs no Purge in Living Donor Liver Transplantation Recipients https://ClinicalTrials.gov/show/NCT02540447 Completed Mansoura University 2014-05-31
NCT02405689 Myocardial Protection and Anesthetic Agents https://ClinicalTrials.gov/show/NCT02405689 Completed Cukurova University 2015-08-31
NCT02390674 Ciclosporin to Reduce Reperfusion Injury in Primary PCI https://ClinicalTrials.gov/show/NCT02390674 Completed Newcastle-upon-Tyne Hospitals NHS Trust 2017-04-30
NCT03386435 The Effect of Remote Ischemic Preconditioning in Living Donor Hepatectomy https://ClinicalTrials.gov/show/NCT03386435 Completed Asan Medical Center 2017-08-31
NCT02290080 Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers https://ClinicalTrials.gov/show/NCT02290080 Completed Karolinska Institutet 2015-12-31
NCT02286544 Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers https://ClinicalTrials.gov/show/NCT02286544 Completed Karolinska Institutet 2015-12-31
NCT02251041 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL) https://ClinicalTrials.gov/show/NCT02251041 Completed Universitaire Ziekenhuizen Leuven 2019-02-28
NCT02149316 Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery https://ClinicalTrials.gov/show/NCT02149316 Completed Chinese Academy of Medical Sciences, Fuwai Hospital 2016-02-29
NCT02134314 C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI https://ClinicalTrials.gov/show/NCT02134314 Completed Cedars-Sinai Medical Center 2017-03-13
NCT02127996 GLP-1 Loading During Elective Percutaneous Coronary Intervention https://ClinicalTrials.gov/show/NCT02127996 Active, not recruiting Papworth Hospital NHS Foundation Trust 2017-03-31
NCT02122484 Colchicine in Coronary Artery Bypass Graft (CABG) https://ClinicalTrials.gov/show/NCT02122484 Completed G.Gennimatas General Hospital 2014-06-30
NCT02118753 The Effect of EPLerenone on Ischemia Reperfusion Injury in Human myoCARDium https://ClinicalTrials.gov/show/NCT02118753 Completed Radboud University 2015-12-31
NCT01295567 Can Dipyridamole Induce Protection Against Ischemia and Reperfusion Injury in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG)? https://ClinicalTrials.gov/show/NCT01295567 Completed Radboud University 2012-02-29
NCT01978132 Primary Hyperaldosteronism and Ischemia-reperfusion Injury https://ClinicalTrials.gov/show/NCT01978132 Completed Radboud University 2017-05-01
NCT01905501 Sevoflurane Protective Effect on Ischemia-reperfusion Injury. Multicenter, Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT01905501 Completed Regina Elena Cancer Institute 2014-09-30
NCT01887171 Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus https://ClinicalTrials.gov/show/NCT01887171 Completed Republican Scientific and Practical Center for Organ and Tissue Transplantation 2014-07-31
NCT01886443 Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers https://ClinicalTrials.gov/show/NCT01886443 Completed Universitaire Ziekenhuizen Leuven 2014-04-30
NCT01882179 Early Mineralocorticoid Receptor Antagonist Treatment to Reduce Myocardial Infarct Size https://ClinicalTrials.gov/show/NCT01882179 Completed University College, London 2016-05-31
NCT01864252 Investigation Into the Role of GTN & RIPC in Cardiac Surgery https://ClinicalTrials.gov/show/NCT01864252 Completed University College, London 2018-10-31
NCT01780740 Statin Therapy In Atrial Refractoriness and Reperfusion Injury https://ClinicalTrials.gov/show/NCT01780740 Completed University of Oxford 2014-08-31
NCT01756508 Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury https://ClinicalTrials.gov/show/NCT01756508 Completed Russian Academy of Medical Sciences 2017-04-15
NCT01739088 Pediatric Remote Ischemic Pre-conditioning Prior to Complex Cardiac Surgery https://ClinicalTrials.gov/show/NCT01739088 Completed University of Alberta 2017-03-31
NCT02709798 ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction https://ClinicalTrials.gov/show/NCT02709798 Completed Beijing Anzhen Hospital 2018-02-28
NCT01731457 Limitation of Ischemic Injury of a Kidney Stored in Machine Perfusion in Hypothermia - Evaluation of the Impact on Kidney Allograft Function https://ClinicalTrials.gov/show/NCT01731457 Completed Medical University of Warsaw 2014-02-28
NCT01680601 Remote Ischaemic Preconditioning in Children Undergoing Cardiac Surgery https://ClinicalTrials.gov/show/NCT01680601 Completed NHS Greater Glasgow and Clyde 2015-03-31
NCT01666587 Ischemia Reperfusion: Prostaglandins and Antioxidants https://ClinicalTrials.gov/show/NCT01666587 Completed University of Essex 2013-04-30
NCT01638624 The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury https://ClinicalTrials.gov/show/NCT01638624 Completed Diskapi Teaching and Research Hospital 2012-10-31
NCT01637038 The Effect of Remote Ischemic Postconditioning on Liver Graft and Renal Function in Patients Undergoing Living-related Liver Transplantation https://ClinicalTrials.gov/show/NCT01637038 Completed Samsung Medical Center 2013-02-28
NCT01610401 The Metformin-FMD Trial https://ClinicalTrials.gov/show/NCT01610401 Completed Radboud University 2013-01-31
NCT01601795 Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit) https://ClinicalTrials.gov/show/NCT01601795 Completed University Hospital, Basel, Switzerland 2014-01-31
NCT01584453 Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT01584453 Completed Barts & The London NHS Trust 2013-11-30
NCT01572909 Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events https://ClinicalTrials.gov/show/NCT01572909 Completed Stealth BioTherapeutics Inc. 2014-11-30
NCT01499979 Hypothermic Perfusion During Hemihepatectomy https://ClinicalTrials.gov/show/NCT01499979 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2015-05-31
NCT01483755 Delayed Postconditioning https://ClinicalTrials.gov/show/NCT01483755 Completed Hospices Civils de Lyon 2012-06-30
NCT01481974 Safety and Efficacy of Treprostinil in Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplantation https://ClinicalTrials.gov/show/NCT01481974 Active, not recruiting University of Pittsburgh 2020-12-31
NCT01454128 The Role of Exercise-Periodic-Breathing (EPB) in Impaired Ventilation Regulation Dysfunction in Heart Failure Patients https://ClinicalTrials.gov/show/NCT01454128 Completed Chang Gung Memorial Hospital 2013-03-31
NCT01430156 Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation https://ClinicalTrials.gov/show/NCT01430156 Completed University of Edinburgh 2013-06-30
NCT01379261 Efficacy of Endovascular Catheter Cooling Combined With Cold Saline for the Treatment of Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT01379261 Completed Region Skane 2013-09-30
NCT01374321 Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT01374321 Completed Hoffmann-La Roche 2013-09-30
NCT01363687 The Effect of Remote Postconditioning on Graft Function in Patients Undergoing Living-related Kidney Transplantation https://ClinicalTrials.gov/show/NCT01363687 Completed Samsung Medical Center 2012-05-31
NCT01354808 ACCEL-LOADING-ACS Study https://ClinicalTrials.gov/show/NCT01354808 Completed Gyeongsang National University Hospital 2012-07-31
NCT04307290 Dexmedetomidine on Tourniquet Induced -Systemic Effects https://ClinicalTrials.gov/show/NCT04307290 Completed Wonkwang University Hospital 2020-02-10
NCT04284592 Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery https://ClinicalTrials.gov/show/NCT04284592 Completed INCLIVA 2015-06-30
NCT03995732 Efficacy and Safety Evaluation of PC-SOD for Injection in Reducing Myocardial Reperfusion Injury https://ClinicalTrials.gov/show/NCT03995732 Recruiting Beijing Tide Pharmaceutical Co., Ltd 2020-10-31
NCT03978065 The Renal Transplant Outcome Prediction and Validation Study https://ClinicalTrials.gov/show/NCT03978065 Active, not recruiting Medical University Innsbruck 2020-03-31
NCT03900390 The Study of Potency of Cross-preconditioning to Prevent Ischemic-reperfusion Injury for Heart Transplantation Recipient https://ClinicalTrials.gov/show/NCT03900390 Recruiting First Affiliated Hospital, Sun Yat-Sen University 2022-07-07
NCT03848780 Desflurane Preconditioning in Hepatectomies https://ClinicalTrials.gov/show/NCT03848780 Completed Aristotle University Of Thessaloniki 2018-06-30
NCT03818126 The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement https://ClinicalTrials.gov/show/NCT03818126 Completed American Heart of Poland 2018-06-30
NCT03806504 High PEEP Application Following Pulmonary Thromboendarterectomy; Does it Have Any Impact on Outcome? https://ClinicalTrials.gov/show/NCT03806504 Recruiting Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital 2019-07-01
NCT03772054 Sevoflurane vs Propofol Effect on Endothelial Damage Markers After Knee Ligament Surgery. https://ClinicalTrials.gov/show/NCT03772054 Completed University of Chile 2019-12-11
NCT03743584 Hypothermia After Cardiac Arrest - Effects on Myocardial Function and Inflammatory Response. https://ClinicalTrials.gov/show/NCT03743584 Recruiting Oslo University Hospital 2020-12-31
NCT03663543 Intravenous Estrogen in Kidney Transplant Study https://ClinicalTrials.gov/show/NCT03663543 Recruiting University of Pennsylvania 2022-01-31
NCT03541239 Immune Modulation by Ischemic Pre-conditioning in Healthy Individuals: Intracellular Signalling in Regulatory Cells https://ClinicalTrials.gov/show/NCT03541239 Completed University of Aarhus 2016-07-19
NCT03535623 RIPC During Free Flap With Preoperative Radiotherapy https://ClinicalTrials.gov/show/NCT03535623 Recruiting Seoul National University Hospital 2020-04-01
NCT03500783 Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT03500783 Completed Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-11-30
NCT03482544 The Effect of Pregabalin Given Preoperatively on the Tourniquet Induced Ischemia-reperfusion https://ClinicalTrials.gov/show/NCT03482544 Completed Baskent University 2018-10-30
NCT03447834 EUROpean Intracoronary Cooling Evaluation in Patients With ST-elevation Myocardial Infarction. https://ClinicalTrials.gov/show/NCT03447834 Recruiting Catharina Ziekenhuis Eindhoven 2021-04-01
NCT01260285 The Safety of Vardenafil in Patients Undergoing Cardiac Surgery https://ClinicalTrials.gov/show/NCT01260285 Completed McGuire Research Institute 2011-10-31
NCT01223326 N-acetylcysteine to Reduce Ischemia/Reperfusion Injury in Liver Resection https://ClinicalTrials.gov/show/NCT01223326 Completed Clinica Universidad de Navarra, Universidad de Navarra 2007-10-31
NCT01208727 Post Cond No Reflow https://ClinicalTrials.gov/show/NCT01208727 Completed Hospices Civils de Lyon 2009-04-30
NCT01172171 The Effect of Melatonin on Ischemia-reperfusion Injury Following Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT01172171 Completed Herlev Hospital 2016-06-30
NCT01167569 Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients https://ClinicalTrials.gov/show/NCT01167569 Completed Rutgers, The State University of New Jersey 2013-04-30
NCT01144585 Effects of Remote Ischemic Preconditioning and Postconditioning on Lung Injury During Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT01144585 Completed Seoul National University Hospital 2010-11-30
NCT01113008 Remote Ischemic Postconditioning in Humans https://ClinicalTrials.gov/show/NCT01113008 Completed Hospital Universitario Virgen de la Victoria 2012-02-29
NCT01073202 Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation https://ClinicalTrials.gov/show/NCT01073202 Completed Shanghai Jiao Tong University School of Medicine 2008-04-30
NCT01040013 Gut Oxygenation and Laparoscopy https://ClinicalTrials.gov/show/NCT01040013 Completed University of Milano Bicocca 2009-03-31
NCT01004289 POSTconditioning During Coronary Angioplasty in Acute Myocardial Infarction Study https://ClinicalTrials.gov/show/NCT01004289 Completed University of Padova 2010-01-31
NCT00995670 Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins https://ClinicalTrials.gov/show/NCT00995670 Completed VA Office of Research and Development 2013-09-30
NCT00994981 Magnesium Administration in Liver Transplantation and Reperfusion Injury https://ClinicalTrials.gov/show/NCT00994981 Completed The Catholic University of Korea 2008-09-30
NCT00987974 Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury https://ClinicalTrials.gov/show/NCT00987974 Completed Radboud University 2010-02-28
NCT00948194 Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver Transplantation https://ClinicalTrials.gov/show/NCT00948194 Completed University of Colorado, Denver 2015-12-31
NCT00924118 Sodium Nitrite in Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT00924118 Completed Johns Hopkins University 2016-06-30
NCT00881686 Myocardial Protection With Adenosine Preconditioning https://ClinicalTrials.gov/show/NCT00881686 Completed Xijing Hospital 2008-12-31
NCT00865722 Remote Postconditioning in Patients With Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention (PCI) https://ClinicalTrials.gov/show/NCT00865722 Completed IRCCS Policlinico S. Matteo 2012-05-31
NCT00845364 Metabolic Support With Perhexiline to Protect Myocardium Undergoing Coronary Artery Surgery https://ClinicalTrials.gov/show/NCT00845364 Completed University Hospital Birmingham 2010-04-30
NCT02833688 Effects of Dexmedetomidine on the Liver Injury After Hepatectomy https://ClinicalTrials.gov/show/NCT02833688 Completed Chinese PLA General Hospital 2017-01-26
NCT02648958 Effect of Dexmedetomidine on Ischemia-Reperfusion Injury in Lower Extremity Operations https://ClinicalTrials.gov/show/NCT02648958 Completed Yonsei University 2017-07-31
NCT03068689 Remote Ischaemic PreConditioning (RIPC) in Partial Nephrectomy for the Prevention of Ischemia/Reperfusion Injury https://ClinicalTrials.gov/show/NCT03068689 Recruiting University Hospital, Basel, Switzerland 2020-08-31
NCT02512640 Comparison of Oxidative Stress Changes in Different Ventilation Strategies During Gynecologic Laparoscopic Surgery https://ClinicalTrials.gov/show/NCT02512640 Completed Chang Gung Memorial Hospital 2013-08-31
NCT02342522 Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI) https://ClinicalTrials.gov/show/NCT02342522 Completed University College, London 2019-03-31
NCT02151877 Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT02151877 Completed Advocate Health Care 2018-08-15
NCT00778323 Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery https://ClinicalTrials.gov/show/NCT00778323 Completed Xijing Hospital 2008-10-31
NCT00627809 Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT00627809 Completed Istanbul University 2008-01-31
NCT00623142 The Protective Effects Of Treatment With Hyperbaric Oxygen Prior To Bypass Heart Surgery https://ClinicalTrials.gov/show/NCT00623142 Completed Hull University Teaching Hospitals NHS Trust 2007-01-31
NCT00609388 Tacrolimus During the Implantation and the Effect on Ischemia-reperfusion Injury in Liver Transplantation https://ClinicalTrials.gov/show/NCT00609388 Completed Medical University of Vienna 2010-12-31
NCT00586820 Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI https://ClinicalTrials.gov/show/NCT00586820 Completed Mayo Clinic 2012-01-31
NCT00582010 Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation https://ClinicalTrials.gov/show/NCT00582010 Completed University of Alabama at Birmingham 2009-03-31
NCT00516711 Role of Volatile Anesthetics for Hepatic Protection https://ClinicalTrials.gov/show/NCT00516711 Completed University of Zurich 2007-12-31
NCT00484575 Inhaled Sevoflurane Compared to Intravenous Sedation Post Coronary Artery Bypass Grafting https://ClinicalTrials.gov/show/NCT00484575 Completed Karolinska Institutet 2008-10-31
NCT00457652 Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury? https://ClinicalTrials.gov/show/NCT00457652 Completed Radboud University 2007-09-30
NCT00457405 Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury? https://ClinicalTrials.gov/show/NCT00457405 Completed Radboud University 2007-10-31
NCT00441597 Does Atorvastatin Reduce Ischemia-Reperfusion Injury in Humans in-Vivo? https://ClinicalTrials.gov/show/NCT00441597 Completed Radboud University 2009-02-28
NCT00430170 Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury? https://ClinicalTrials.gov/show/NCT00430170 Completed Radboud University 2007-03-31
NCT00405015 The Effect of Rosiglitazone on Ischemia-reperfusion-injury Using Annexin A5 Scintigraphy. https://ClinicalTrials.gov/show/NCT00405015 Completed Radboud University 2008-07-31
NCT00402506 A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG https://ClinicalTrials.gov/show/NCT00402506 Completed Medicure NA
NCT00326976 Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury https://ClinicalTrials.gov/show/NCT00326976 Completed Fibrex Medical Research & Development GmbH NA
NCT00286312 Myocardial Infarction Size Reduction With Atorvastatin https://ClinicalTrials.gov/show/NCT00286312 Completed R&D Cardiologie 2008-02-29
NCT00265239 Pilot Study of Edaravone to Treat Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT00265239 Completed Kumamoto University NA
NCT00248040 Reparixin in Prevention of Delayed Graft Function After Kidney Transplantation https://ClinicalTrials.gov/show/NCT00248040 Completed Dompé Farmaceutici S.p.A 2008-05-31
NCT00246740 Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting https://ClinicalTrials.gov/show/NCT00246740 Completed University of Alberta 2008-05-31
NCT00226369 Cylexin for Reduction of Reperfusion Injury in Infant Heart Surgery https://ClinicalTrials.gov/show/NCT00226369 Completed Boston Children’s Hospital NA
NCT00224406 Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation https://ClinicalTrials.gov/show/NCT00224406 Completed Dompé Farmaceutici S.p.A 2007-09-30
NCT00184912 The Effect of Caffeine on Ischemic Preconditioning https://ClinicalTrials.gov/show/NCT00184912 Completed Radboud University NA
NCT00157716 MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery) https://ClinicalTrials.gov/show/NCT00157716 Completed Medicure NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03410576 Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy https://ClinicalTrials.gov/show/NCT03410576 Completed University of Pecs 2015-11-30
NCT03248557 Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death https://ClinicalTrials.gov/show/NCT03248557 Recruiting Hospital San Carlos, Madrid 2020-12-31
NCT03050489 Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG https://ClinicalTrials.gov/show/NCT03050489 Completed St. Petersburg State Pavlov Medical University 2019-05-31
NCT03397732 Perioperative Evaluation of MMP-9-TIMP-1 System in Vascular Surgery Regarding Ischemic-reperfusion Injury https://ClinicalTrials.gov/show/NCT03397732 Completed University of Pecs 2013-06-01
NCT03389607 The Role of SCUBE-1 in Ischemia-reperfusion Injury https://ClinicalTrials.gov/show/NCT03389607 Completed Diskapi Yildirim Beyazit Education and Research Hospital 2018-09-01
NCT03354767 The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery https://ClinicalTrials.gov/show/NCT03354767 Completed Imperial College London 2014-10-31
NCT01944605 Intestinal Ischemia as a Stimulus for Systemic Inflammatory Response After Cardiac Arrest https://ClinicalTrials.gov/show/NCT01944605 Completed Virginia Commonwealth University 2014-03-30
NCT01932918 Antinociceptive Modalities on Ischemia Reperfusion Injury https://ClinicalTrials.gov/show/NCT01932918 Completed National Taiwan University Hospital 2015-07-31
NCT01700660 Reperfusion-induced Self-antigen Excretion Following Major Liver Surgery https://ClinicalTrials.gov/show/NCT01700660 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2014-12-31
NCT01660516 Effect of Tea on Endothelial Function and Ischaemia-reperfusion Injury https://ClinicalTrials.gov/show/NCT01660516 Completed Radboud University 2012-02-29
NCT01606410 The Impact of Age and Fitness on Reperfusion Injury and Ischemic Preconditioning to Prevent This Injury https://ClinicalTrials.gov/show/NCT01606410 Completed Radboud University 2013-11-30
NCT01486212 Ischemia-reperfusion Injury Model on Healthy Volunteers and Measurement of Oxidative and Inflammatory Markers https://ClinicalTrials.gov/show/NCT01486212 Completed Herlev Hospital 2011-12-31
NCT01414452 Role of Adiponectin and Endothelial Progenitor Cells in Reperfusion Injury in Patients With Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT01414452 Completed Universiteit Antwerpen 2012-12-31
NCT04397939 Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19 https://ClinicalTrials.gov/show/NCT04397939 Recruiting Icahn School of Medicine at Mount Sinai 2021-03-31
NCT04316468 Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation https://ClinicalTrials.gov/show/NCT04316468 Enrolling by invitation Mayo Clinic 2020-12-31
NCT04257240 Recurrence of Liver Malignancy After Ischemia/Reperfusion Injury https://ClinicalTrials.gov/show/NCT04257240 Completed Aretaieion University Hospital 2012-12-31
NCT03939338 Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients https://ClinicalTrials.gov/show/NCT03939338 Recruiting Beijing Friendship Hospital 2021-08-31
NCT03838289 Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy https://ClinicalTrials.gov/show/NCT03838289 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2020-12-31
NCT03522116 Relationship Between CMR-derived Parameters of Ischemia / Reperfusion Injury and Timing of CMR in STEMI https://ClinicalTrials.gov/show/NCT03522116 Completed Centre Hospitalier Universitaire Vaudois 2016-08-01
NCT03510793 Microcirculation and Anesthesia in Vascular Surgery https://ClinicalTrials.gov/show/NCT03510793 Completed Università Politecnica delle Marche 2017-11-30
NCT04205253 Tongue Depressor-related Ischemia-Reperfusion Injury in Tongue https://ClinicalTrials.gov/show/NCT04205253 Completed Selcuk University 2019-04-01
NCT00698399 Serum Markers of Ischemia Reperfusion Injury in Liver Transplant Patients https://ClinicalTrials.gov/show/NCT00698399 Completed Vanderbilt University Medical Center 2010-02-02
NCT00529607 Diagnostics for the Reperfusion Injury Following MI https://ClinicalTrials.gov/show/NCT00529607 Completed RWTH Aachen University 2009-03-31
NCT00385151 To Compare the Ischemic Pre-conditioning and Post-conditioning on Reperfusion Injury in Humans. https://ClinicalTrials.gov/show/NCT00385151 Completed Emory University NA
NCT00229047 Ischemia and Reperfusion Injury in the Human: An Observational Study https://ClinicalTrials.gov/show/NCT00229047 Completed Lawson Health Research Institute 2010-12-31
NCT00184821 Ischemic Injury and Ischemic Preconditioning in Diabetes https://ClinicalTrials.gov/show/NCT00184821 Completed Radboud University NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03531151 MRI of Myocardial Infarction https://ClinicalTrials.gov/show/NCT03531151 Recruiting University of Pennsylvania 2023-03-31